Laboratory of Microbial Genomics

Anahit Sedrakyan

Head of the laboratory, PhD

Laboratory members

Alvard Hovhannisyan, PhD
Karine Arakelova
Magdalina Zakharyan
Junior researcher
Shoghik Hakobyan
PhD studentt

General information

The research activities of the laboratory are focused on the most common foodborne bacterial pathogens circulating
in Armenia for developing the appropriate strategies to control the most common foodborne diseases in Armenia.
One of the research tasks of the laboratory is to study the potential of bacteriophages showing activity against
multidrug-resistant isolates of bacterial pathogens circulating in Armenia to control bacterial infections and spread of
antimicrobial resistance.

Current Research Projects

  • In-depth characterization of human isolates of the most common in Armenia bacterial enteric pathogens displaying
    multi-drug resistance phenotype to improve antimicrobial therapy approaches and trace the emergence and lineage of
    clinically problematic and/or epidemiologically successful clones of these pathogens in Armenia.

Selected publications

  1. Sedrakyan A, Ktsoyan Z, Arakelova K, Gevorgyan Z, Zakharyan M, Hakobyan S, Hovhannisyan A, Arakelyan
    A, Aminov R. Molecular Epidemiology and Virulence of Non-Typhoidal Salmonella in Armenia. Int J Mol Sci.
    2022 Aug 18;23(16):9330. doi: 10.3390/ijms23169330
    2. Sedrakyan AM, Ktsoyan ZA, Arakelova KA, Zakharyan MK, Hovhannisyan AI, Gevorgyan ZU, Mnatsakanyan
    AA, Kakabadze EG, Makalatia KB, Chanishvili NA, Pirnay JP, Arakelyan AA, Aminov RI. Extended-Spectrum
    β-Lactamases in Human Isolates of Multidrug-Resistant Non-typhoidal Salmonella enterica. Front Microbiol.
    2020 Dec 22;11:592223. doi: 10.3389/fmicb.2020.592223
    3. Ktsoyan Z, Budaghyan L, Agababova M, Mnatsakanyan A, Arakelova K, Gevorgyan Z, Sedrakyan A,
    Hovhannisyan A, Mkrtchyan M, Zakharyan M, Arakelyan A, Aminov R. Potential Involvement of Salmonella
    Infection in Autoimmunity. Pathogens. 2019 Jul 3;8(3):96. doi: 10.3390/pathogens8030096
    4. Ktsoyan ZA, Mkrtchyan MS, Zakharyan MK, Mnatsakanyan AA, Arakelova KA, Gevorgyan ZU, Ktsoyan LA,
    Sedrakyan AÌ, Hovhannisyan AI, Ghazaryan KA, Boyajyan AS, Aminov RI. Differential induction of total IgE
    by two Salmonella enterica serotypes. Front Cell Infect Microbiol. 2015 May 26;5:43. doi:
    5. Ktsoyan ZA, Beloborodova NV, Sedrakyan AM, Osipov GA, Khachatryan ZA, Manukyan GP, Arakelova KA,
    Hovhannisyan AI, Arakelyan AA, Ghazaryan KA, Zakaryan MK, Aminov RI. Management of familial
    Mediterranean fever by colchicine does not normalize the altered profile of microbial long chain fatty acids in the
    human metabolome. Front Cell Infect Microbiol. 2013 Jan 28;3:2. doi: 10.3389/fcimb.2013.00002